Professor Mladen Krajačić, Professor Emeritus at the Faculty of Science of the University of Zagreb and professor at TMA, was invited as a plenary speaker at the 11th Symposium of Students of Biology (SiSB). As part of the event, an interview with Professor Krajačić was recorded and published by the Croatian media portal tportal.hr.

The interview addresses one of the major challenges of modern medicine: antibiotic resistance, and the potential role of bacteriophages in the treatment of bacterial infections.

In the interview, Professor Krajačić highlights the main advantages of bacteriophages:

• High specificity: Unlike broad-spectrum antibiotics, phages target specific bacteria or bacterial strains.
• Protection of microflora: Due to their specificity, phages do not damage the normal human microflora.
• Efficacy against resistant bacteria: The use of phages is particularly important when pathogenic bacteria are resistant to available antibiotics.
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Despite these advantages, the practical application of phage therapy is associated with several challenges, including the availability of research and clinical infrastructure, as well as the need for qualified interdisciplinary teams.

During the interview, Professor Krajačić also discussed the use of modified viruses in gene therapy, targeted drug delivery approaches, vaccine development, and oncolytic therapy (the selective destruction of tumor cells).

To read the full interview, please follow the link :