Investigation of Foodborne and waterborne bacterial pathogens causing gastrointestinal tract infections

Scientific Investigator: Taras Gabisonia Project Investigator: 2019-03-18 Project Duration: 6 months

Students were involved in the project realization.
According to World Health Organization (WHO) data, every year approximately 2 billion people are affected by intestinal infections all over the world. Foodborne and waterborne pathogens continue to be one of the major causes of morbidity and mortality, and they also cause significant morbidity in developed nations and lead to about 1.8 million deaths globally every year. Due to these problems microbiological and molecular-biological investigation of bacterial pathogens, causing intestinal infections is very important. One of the major food and waterborne pathogens are different species of Salmonella, Shigella and pathogenic Escherichia coli.
As reported by the National Centre for Disease Control of Georgia about 60 000 cases of intestinal infections and 30 000 presumptive infectious diarrheal diseases are identified every year in Georgia.
Monitoring and control of foodborne and waterborne pathogens will reduce their occurrence in the environment and food line and therefore the risk of spreading diseases caused by these pathogens will also decrease.
Because of the unique resistance patterns of bacterial strains to antibiotics, the determination of sensitivity to antimicrobial preparations is very important for monitoring of pathogens and can be used as a necessary epidemiological marker for these pathogens.
The aim of the project is to identify bacterial pathogens causing intestinal infections in clinical specimens, as well as food products (meat, eggs) and water samples and to determine the sensitivity of isolates strains to antibiotics.
To achieve this goal, the following actions will be performed:

  • Isolation and identification of bacterial pathogens causing intestinal infections from clinical samples using morphological, biochemical, and serological methods;
  • Isolation and identification of bacterial pathogens causing intestinal infections from food products and water samples using morphological, biochemical, and serological methods;
  • Investigation of antibiotic resistance profiles of isolated strains. Investigation of Foodborne and waterborne bacterial pathogens causing gastrointestinal tract infections.